Effect of drought stress, Seeding density and cultivar was studied on the growth, development and yield of dryland wheat in Mashhad and Shirvan. Treatments (in Mashhad) were consisted of draught stress in grain filling period (with and without stress), density (85,103,175 kg\ha) and cultivar (Sarday and Sabalan) in a spilt factorial design with three replications. In Shirvan (rainfed), treatments were Seeding density (70,100,130,160,190 kg\ha) and cultivar (sardary and sabalan) in a factorial design with three replications. Results showed that, in Mashhad, drought stress decreased anthesis to maturity period, spike number thousand kernel weight, seed and biological yield, and harvest index and increased leaf area index, total and dead dry matter at anthesis. Effects of Seeding density on spike number, seed and biological yield and thousand kernel weights followed a diminishing trend after a maxmium. In Mashhad and for all of the traits (in except of tiller number), Sabalan was supperior over Sarday. In Shirvan, increasing Seeding density resulted in decreasing of tiller number, kernel number per spike, harvest index and increasing of leaf area index, total and dead dry matter at anthesis, spike number and seed yield. Superiority of Sabalan was ,also obvious in rainfed condition of Shirvan.